Recommended Dietary Allowance: Vitamin K has not been established by the FDA as being necessary to human nutrition; however, some sources consider 300 to 500 micrograms daily adequate.
Therapeutic Dose: In some instances one milligram is given to infants shortly after birth to prevent hemorrhaging. Mothers in labor are sometimes given 10 to 20 milligrams. Vitamin K, administered through injection, should be dispensed by physicians who have had experience with it.
Megadose: Any megadose should be ad ministered only with a physician's discretion. Toxicity
Ten milligrams or more of vitamin K can be toxic to infants. Although natural vitafnin K has no toxic effects in adults, the synthetic variety can be toxic if administered in doses of 30 milligrams or more. Pregnant mothers injected with synthetic vitamin K have experienced flushing, sweating and chest constrictions. In infants the vitamin has produced ker-nicterus (a disease wherein a yellow pigment invades the brain and spinal cord between the second and eighth day after birth); the prognosis for recovery from this disease is poor.
The most noticeable symptoms of a deficiency of vitamin K are decreased clotting time of the blood, excessive bleeding in the muscles, colon or other organs, susceptibility to bruising, nosebleeds, miscarriages and anemia. A deficiency can also manifest in intestinal disorders, such as diarrhea and colitis.
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